Our focus is immunology, because we believe that no other biomedical discipline has greater implications for human health than immunology. By unraveling the complexities of the immune system, LJI researchers are directly tackling an extraordinarily diverse array of diseases, which together account for more than two-thirds of all deaths in the U.S. each year. Such diseases include type 1 diabetes, cancer, COVID-19, rheumatoid arthritis, multiple sclerosis, asthma, allergies, influenza, dengue fever, and many other illnesses. La Jolla Institute is home to four research centers that focus the efforts of collaborative groups of researchers on defined areas of inquiry, to accelerate progress toward the development of new treatments and vaccines to prevent and cure autoimmune conditions, cancer, and infectious disease, and to uncover the largely unexplored sex-specific variables in immune responses. LJI is host to three national databases that give biomedical researchers free access to the world’s largest collection of epitopes and related scientific data and provide insights into how genes act within the immune system to set it in motion. Life without Disease is a pursuit that requires a continually expanding understanding of the immune system, and the ability to translate knowledge and discoveries developed in scientific research into technologies that improve life and health. Learn more at https://www.lji.org
La Jolla Institute for Immunology
Research Services
La Jolla, CA 10,330 followers
Dedicated to understanding the intricacies and power of the immune system; striving toward a Life Without Disease ®.
About us
"Sometimes in science there are so many people trying to answer the same question that it's good to stray off in another direction," Mitchell Kronenberg, Ph.D., LJI Professor. "Taking the road less traveled can bring its voyagers to unexpected - and even groundbreaking - new territory." The La Jolla Institute The La Jolla Institute for Immunology is a non-profit medical research institute dedicated to increasing knowledge and improving human health through studies of the immune system. Our essential purpose is to expand our understanding of how the immune system works and to discover the causes of immune system disorders. The knowledge gained through our biomedical research can, in turn lead to the prevention, treatment and cure of a wide range of human diseases. What is immunology? Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune response. The immune response is the defense system of the body carried out by white blood cells against microbial threats such as a virus infection. Since immunology has an effect on every organ system in our body, there is no biomedical discipline that has greater implications for improving human health. Where is LJI? The La Jolla Institute is located in the University of California San Diego's Science Research Park in a world-class facility covering 145,000 square feet. Our space provides an open laboratory setting that encourages La Jolla Institute for Immunology's highly collaborative research environment.
- Website
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https://www.lji.org
External link for La Jolla Institute for Immunology
- Industry
- Research Services
- Company size
- 201-500 employees
- Headquarters
- La Jolla, CA
- Type
- Nonprofit
- Founded
- 1988
Locations
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Primary
9420 Athena Circle
La Jolla, CA 92037, US
Employees at La Jolla Institute for Immunology
Updates
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In our cells, molecules called phosphate groups are constantly attaching to—or detaching from—proteins. These “post-translational modifications” alter how our proteins function. Recently, LJI researchers have shared a new, rapid method for studying post-translational modifications. “We can now do this functional testing for 10,000 or more phosphorylation sites at a time,” says LJI and Global Autoimmune Institute Assistant Professor Samuel Myers, Ph.D. This method is a major leap forward for scientists investigating how proteins do their jobs in the immune system. “This method basically creates an entire new kind of world of experiments that people can do,” adds Myers. #MassSpec #BioChemistry #NatureMethods #proteins #translational #immunesystem https://lnkd.in/g8yzyiAd
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Today, Apr. 29, is the official International Day of Immunology! What a nice excuse to celebrate immune system research. We recently celebrated #DayofImmunology with a "Build Your Science" Lego competition here at LJI. All #Lego models were truly inspirational! 🤩 Cheers to our winners: 🏆 Most scientifically accurate build: Glycoprotein with Antibody by Theresa Gewering 🏆 Best group build: Lab Mouse/Rat by Miriam Muller, Erin Moore, and Amparo Martínez-Pérez 🏆 Best individual build: Acquired Cells on FlowJo from a Flow Cytometer by Calvin Ha 🏆 Best build by a non-scientist: Manhattan Plot by Sonja Arnold #Lego #ImmuneCells #DayOfImmunology #ImmuneSystem #antibody #mouse #rat #cheese #cells #ManhattanPlot
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Happy #DayofImmunology! The immune system is amazing — and many of our body's immune defense strategies are still a mystery. LJI's astounding collection of top-notch tools, like those within our cutting-edge Flow Cytometry Core, have uncovered immune cells no one has ever seen before! Check out our new Immune Matters article to learn more and watch behind-the-scenes footage of this research in action! https://lnkd.in/g3BUzNXx #SanDiego #Immunology #ImmuneSystem #Health #Medicine #FlowCytometry #Biology #CellularBiology #Tech #SARSCoV2
The wild world of flow cytometry
https://mag.lji.org
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“Where I grew up, you are primed to believe you have a task in life—that we’re each given a responsibility,” says former LJI postdoc Rosa Isela Gálvez, Ph.D. “I can’t fix the world, but it’s my responsibility to do something of value.” Learn why Dr. Gálvez chose to work at LJI — and how LJI trainees have gone on to advance immune system research. Michael Norris , Camila Coelho, PhD MBA , Stephane Becart #LJIalumni #alumni #careerlaunch #trainingground #STEM #ScienceCareers #Science #Immunology #Postdoc #GradSchool #MolecularBiology #CellularBiology #Virology #VaccineResearch #AutoimmuneDisease https://bit.ly/4aFJHk5
Training the best
https://mag.lji.org
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LJI scientists are pioneering new ways to use #DataScience to fight disease. Check out our latest Immune Matters articles to learn what's next as scientists use artificial intelligence and computational biology to understand the human immune system. https://mag.lji.org/ #Science #STEM #SanDiego #Immunology #ImmuneSystem #Health #Medicine #DataScience #CompBio #DataAnalysis #SARSCoV2
Immune Matters Magazine - Spring 2024
https://mag.lji.org
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LJI’s Flow Cytometry Core, which provides cutting-edge research services, has been named a BD Biosciences “Center of Excellence” 💫 Along with this distinction, the LJI Flow Core has brought in a sophisticated instrument for immune cell research: the BD FACSDiscover™ S8 Cell Sorter. This novel technology adds to the already impressive collection of machines run by Flow Core Senior Director Cheryl Kim and her team. “This is an exciting opportunity,” says Kim. “We’ve got LJI scientists who are interested in using this cell sorter right away.” Thanks to support from generous donors, including The Conrad Prebys Foundation, the LJI Flow Core houses four cell sorters that can detect over 28 different colors of fluorescent antibodies. Scientists can tag specific proteins with this wide array of colors to find rare types of immune cells. “LJI’s Flow Cytometry Core is an amazing resource for LJI scientists—and for our scientific collaborators around the globe,” says LJI Chief Scientific Officer Shane Crotty, Ph.D. Photo: LJI Flow Cytometry Specialist Kirby Inocente (left) analyzes samples provided by LJI Postdoctoral Fellow Simon BRUNEL Ph.D. (right). Read more: https://lnkd.in/g56GEaxE
LJI home to new “Center of Excellence”
https://www.lji.org
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On April 10th, LJI Professor, President & CEO Erica Ollmann Saphire, PhD, MBA, joined an esteemed selection of leaders in biomedical research and healthcare at Women's Health Access Matters #3Not30 Initiative dedicated to accelerating women’s health research and investment. In her remarks, Dr. Saphire emphasized the collaboration necessary to establish a blueprint for transforming scientific research by prioritizing a sex-based lens—one that takes into account the dynamic interplay between biology and sex. It is this foundational belief that prompted us to establish the groundbreaking Center for Sex-based Differences in the Immune System, which aims to reshape the landscape of scientific research by exploring sex as a critical variable in human health. In just a few short years, our endeavors have already borne fruit, with landmark discoveries shedding new light on the genetic, transcriptional, and metabolic disparities that underpin sex-based differences in immune function. We've uncovered the profound reality that men and women activate distinct sets of genes, and their immune systems harbor unique populations of cells. These disparities serve as the linchpin for unlocking innovative therapies and cures across a wide spectrum of ailments, ranging from autoimmune disorders to neurodegenerative afflictions. Most importantly, Dr. Saphire's closing remarks stressed that when we target resources towards women’s health, the rewards will be profound, benefitting BOTH women and men. Learn more about our center https://lnkd.in/gfRZvREy #ImmuneSystem #WomensHealth #MensHealth #WomensHealthResearch #WHAM
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On April 7th, Team LJI participated in Curebound's San Diego Padres #PedaltheCause, where over 4,100 participants were welcomed to Petco Park to walk, run and ride for a cure by raising funds for the innovative cancer research happening at LJI and several other research institutes in San Diego. We want to extend a heartfelt thank you to our sponsors Quantabio, New England Biolabs, and Element Biosciences for their support. We had a great time celebrating and remembering why we are all part of this community – to accelerate cures for cancer.
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How does #immunity differ between men and women? LJI Associate Professor Sonia Sharma leads an important LJI initiative to reveal sex-based differences in the immune system. This work is critical for combating #asthma #cancer, #COVID19 and more. In fact, Dr. Sharma and Priyanka Saminathan, Ph.D., from LJI's Sharma Lab, have been investigating an "Achilles heel" that leaves men more susceptible to COVID-19, compared with women. Their work has revealed how an enzyme called ADA2 may pose a challenge for the male immune system. Dr. Saminathan will present their findings at the AAI IMMUNOLOGY 2024 meeting on May 7. Learn more about breakthroughs from LJI's Center for Sex-Based Differences in the Immune System and through LJI's partnership with Women's Health Access Matters: https://bit.ly/3PXLGIb #AAI2024 #immunesystem
Center for Sex-based Differences in the Immune System
https://www.lji.org